Cancer Immunotherapy: Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy (Adv. Mater. 16/2020)

In article number 1907953, Jae Hyung Park and co‐workers present the potential of necroptosis‐inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage‐associated molecular patterns and tumor‐associated antigens by inducing cell membrane...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2020-04, Vol.32 (16), p.n/a
Main Authors: Um, Wooram, Ko, Hyewon, You, Dong Gil, Lim, Seungho, Kwak, Gijung, Shim, Man Kyu, Yang, Suah, Lee, Jeongjin, Song, Yeari, Kim, Kwangmeyung, Park, Jae Hyung
Format: Article
Language:English
Subjects:
damage‐associated molecular patterns
immune checkpoint blockade
necroptosis
reactive oxygen species
sonodynamic therapy
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Summary:In article number 1907953, Jae Hyung Park and co‐workers present the potential of necroptosis‐inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage‐associated molecular patterns and tumor‐associated antigens by inducing cell membrane rupture, facilitating efficient maturation of the dendritic cell for antitumor immune response.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202070121