Cancer Immunotherapy: Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy (Adv. Mater. 16/2020)

In article number 1907953, Jae Hyung Park and co‐workers present the potential of necroptosis‐inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage‐associated molecular patterns and tumor‐associated antigens by inducing cell membrane...

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Published in:Advanced materials (Weinheim) 2020-04, Vol.32 (16), p.n/a
Main Authors: Um, Wooram, Ko, Hyewon, You, Dong Gil, Lim, Seungho, Kwak, Gijung, Shim, Man Kyu, Yang, Suah, Lee, Jeongjin, Song, Yeari, Kim, Kwangmeyung, Park, Jae Hyung
Format: Article
Language:English
Subjects:
damage‐associated molecular patterns
immune checkpoint blockade
necroptosis
reactive oxygen species
sonodynamic therapy
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container_issue 16
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container_title Advanced materials (Weinheim)
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creator Um, Wooram
Ko, Hyewon
You, Dong Gil
Lim, Seungho
Kwak, Gijung
Shim, Man Kyu
Yang, Suah
Lee, Jeongjin
Song, Yeari
Kim, Kwangmeyung
Park, Jae Hyung
description In article number 1907953, Jae Hyung Park and co‐workers present the potential of necroptosis‐inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage‐associated molecular patterns and tumor‐associated antigens by inducing cell membrane rupture, facilitating efficient maturation of the dendritic cell for antitumor immune response.
doi_str_mv 10.1002/adma.202070121
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source Wiley-Blackwell Read & Publish Collection
subjects damage‐associated molecular patterns
immune checkpoint blockade
necroptosis
reactive oxygen species
sonodynamic therapy
title Cancer Immunotherapy: Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy (Adv. Mater. 16/2020)
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