Loading…
Synthesis and Applications of HexaPHEMP, a Novel Biaryl Diphosphine Ligand
The novel biaryldiphosphine ligand 1 (HexaPHEMP) has been prepared in five steps from commercially available 3,4,5‐trimethylphenol using a concise synthetic route. This approach also allows fine tuning of the ligand's stereoelectronic properties through the variation of the aromatic groups on t...
Saved in:
Published in: | Advanced synthesis & catalysis 2003-01, Vol.345 (1-2), p.300-307 |
---|---|
Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | The novel biaryldiphosphine ligand 1 (HexaPHEMP) has been prepared in five steps from commercially available 3,4,5‐trimethylphenol using a concise synthetic route. This approach also allows fine tuning of the ligand's stereoelectronic properties through the variation of the aromatic groups on the ligating phosphorus atoms. In certain asymmetric hydrogenation processes, catalysts containing this ligand were found to have enhanced activity and selectivity over other biaryldiphosphine‐containing catalysts. |
---|---|
ISSN: | 1615-4150 1615-4169 |
DOI: | 10.1002/adsc.200390025 |