Visible Light‐Induced Aerobic Oxidative −H Arylation of Glycine Derivatives

A direct aerobic oxidative dehydrogenative coupling reaction of glycine derivatives with electron‐rich arenes has been accomplished via the synergistic combination of organic‐dye mediated photoredox catalysis and Lewis acid catalysis. This process exhibits good tolerance of functional groups and pro...

Full description

Saved in:
Bibliographic Details
Published in:Advanced synthesis & catalysis 2018-11, Vol.360 (22), p.4452-4456
Main Authors: Li, Shilin, Yang, Xiaorong, Wang, Yunwei, Zhou, Huang, Zhang, Boyang, Huang, Ganxing, Zhang, Yuan, Li, Ying
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A direct aerobic oxidative dehydrogenative coupling reaction of glycine derivatives with electron‐rich arenes has been accomplished via the synergistic combination of organic‐dye mediated photoredox catalysis and Lewis acid catalysis. This process exhibits good tolerance of functional groups and provides rapid synthesis of arylglycine derivatives at room temperature under an air atmosphere. Moreover, this protocol could be performed on a 10 mmol scale, without obvious reduction of the yield. magnified image
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.201801018