Bright and Specific Fluorescent Sensor for Mercury in Water, Cells, and Tissue

A bright idea: By restricting the rotation between receptor and reporter units of the fluorescent chemosensor Mercury Green 1 (MG1), a remarkably high quantum efficiency is achieved in its Hg2+‐ion‐bound form in water (Φ=0.72). MG1 is specific to environmentally and biologically relevant mercury lev...

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2007-01, Vol.46 (35), p.6658-6661
Main Authors: Yoon, Sungho, Miller, Evan W, He, Qiwen, Do, Patrick H, Chang, Christopher J
Format: Article
Language:English
Subjects:
Animals
Cell Line
Colorimetry
Fishes
fluorescein
fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Heterocyclic Compounds, 1-Ring - chemical synthesis
Humans
Indicators and Reagents
Meat - analysis
mercury
Mercury - analysis
Microscopy, Confocal
sensors
Spectrometry, Fluorescence
Spectrophotometry, Atomic
Water - analysis
Water Pollutants, Chemical - analysis
Xanthenes - chemistry
Xanthones - chemical synthesis
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Summary:A bright idea: By restricting the rotation between receptor and reporter units of the fluorescent chemosensor Mercury Green 1 (MG1), a remarkably high quantum efficiency is achieved in its Hg2+‐ion‐bound form in water (Φ=0.72). MG1 is specific to environmentally and biologically relevant mercury levels (ppm to ppb range), and can assay levels of Hg2+ ion in living cells and in edible fish.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200701785