Mixed metal MgO–ZrO 2 nanoparticle‐catalyzed O‐ tert ‐Boc protection of alcohols and phenols under solvent‐free conditions

An environmentally benign method for O‐tert ‐Boc protection of alcohols and phenols catalyzed by MgO–ZrO 2 nanoparticles under solvent‐free conditions is described. A variety of phenols, alcohols (aliphatic and aromatic) were converted to corresponding O‐tert ‐Boc products in good to excellent yield...

Full description

Saved in:
Bibliographic Details
Published in:Applied organometallic chemistry 2012-08, Vol.26 (8), p.395-400
Main Authors: Gawande, Manoj B., Shelke, Sharad N., Branco, Paula S., Rathi, Anuj, Pandey, Rajesh K.
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An environmentally benign method for O‐tert ‐Boc protection of alcohols and phenols catalyzed by MgO–ZrO 2 nanoparticles under solvent‐free conditions is described. A variety of phenols, alcohols (aliphatic and aromatic) were converted to corresponding O‐tert ‐Boc products in good to excellent yield (50–95%). The present protocol is expedient, simple, and efficient under solvent‐free conditions. The MgO–ZrO 2 Nps are easily prepared from inexpensive precursors, and are reusable, recyclable and chemoselective. Copyright © 2012 John Wiley & Sons, Ltd.
ISSN:0268-2605
1099-0739
DOI:10.1002/aoc.2846