Sjogren's syndrome I. Serologic reactions in patients with Sjogren's syndrome with and without rheumatoid arthritis

• Published in: Arthritis and rheumatism 1960-08, Vol.3 (4), p.287-297
• Main Authors: Bloch, K. J., Wohl, M. J., Ship, I. I., Oglesby, R. B.
• Format: Article
• Language: English
• ISSN: 0004-3591; 1529-0131
• DOI: 10.1002/art.1780030402

Sera from 21 patients with Sjogren's syndrome with and without rheumatoid arthritis were examined. Hypergammaglobulinemia occurred in 71 per cent, the bentonite flocculation test was positive in 95 per cent and sensitized sheep cell agglutination test in 90 per cent of the entire group and in 75 per cent of patients with Sjogren's syndrome without joint involvement. Antinuclear antibody was present in 71 per cent and L.E. cells in 10 per cent. The direct Coombs' test was positive in 25 per cent and thyroglobulin antibodies were found in 14 per cent. Compared to rheumatoid arthritis patients without Sjogren's syndrome, patients in this series were distinguished by an unusually active immunologic response. Esseva examinate specimens de sero ab 21 patientes con syndrome de Sjogren, con e sin arthritis rheumatoide. Hypergammaglobulinemia esseva presente in 71 pro cento del casos. Le test de flocculation a bentonite esseva positive in 95 pro cento del casos. Le test del agglutination de sensibilisate cellulas ovin esseva positive in 90 pro cento de omne le casos e in 75 pro cento del casos sin affection articular. Anticorpore antinucleari esseva presente in 71 pro cento del casos, cellulas de L.E. in 10 por cento. Le directe test de Coombs esseva positive in 25 pro cento, e anticorpore thyroglobulinic esseva trovate in 14 pro cento. In comparation con patientes con arthritis rheumatoide sed sin syndrome de Sjogren, le presente serie se distingueva per un inusualmente active responsa immunologic.