Intradermal hypersensitivity in systemic lupus erythematosus

This is a report of a study of intradermal hypersensitivity to normal leukocytes in patients with systemic lupus erythematosus (SLE). Positive reactions, characterized by induration, edema, and erythema, developed in 15 of 17 SLE patients. This reaction was maximum at 24 hours postinjection. Similar...

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Published in:Arthritis and rheumatism 1961-02, Vol.4 (1), p.64-73
Main Authors: Bennett, J. Claude, Holley, Howard L.
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Language:English
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description This is a report of a study of intradermal hypersensitivity to normal leukocytes in patients with systemic lupus erythematosus (SLE). Positive reactions, characterized by induration, edema, and erythema, developed in 15 of 17 SLE patients. This reaction was maximum at 24 hours postinjection. Similar phenomena were rarely observed in control patients. Histological studies of the reaction site revealed evidence of both Arthus and delayed type hypersensitivity. Iste articulo presenta un studio del hypersensibilitate intradermic pro leucocytos normal in patientes con systemic lupus erythematose. Reactiones positive—characterisate per induration, edema, e erythema—occurreva in dece‐cinque inter dece‐septe patientes. Le reaction esseva maximal 24 horas post le injection. Simile phenomenos esseva observate rarmente in subjectos de controlo. Studios histologic del sitos del reaction revelava signos de hypersensibilitate del typo de Arthus e del typo tardive.
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title Intradermal hypersensitivity in systemic lupus erythematosus
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