HL‐A 27 in reactive arthritis. A study of yersinia arthritis and Reiter's disease

The histocompatibility antigen HL‐A 27 was identified in 43 of 49 patients with yersinia arthritis and in 36 of 40 patients with Reiter's disease, compared with 3 of 20 patients with yersinia infection without arthritis and 14% of the normal Finnish population. HL‐A 2 occurred in patients with...

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Bibliographic Details
Published in:Arthritis and rheumatism 1974-09, Vol.17 (5), p.521-526
Main Authors: Aho, Kimmo, Ahvonen, Paavo, Lassus, Allan, Sievers, Kai, Tiilikainen, Anja
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Arthritis, Infectious - genetics
Arthritis, Infectious - immunology
Arthritis, Infectious - microbiology
Arthritis, Reactive - genetics
Arthritis, Reactive - immunology
Cytotoxicity Tests, Immunologic
Female
Finland
Histocompatibility Antigens - analysis
Homozygote
Humans
Lymphocytes - immunology
Male
Middle Aged
Pasteurella Infections - immunology
Phenotype
Rheumatoid Factor - analysis
Salpingitis - etiology
Skin Manifestations
Urethritis - etiology
Yersinia - isolation & purification
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Summary:The histocompatibility antigen HL‐A 27 was identified in 43 of 49 patients with yersinia arthritis and in 36 of 40 patients with Reiter's disease, compared with 3 of 20 patients with yersinia infection without arthritis and 14% of the normal Finnish population. HL‐A 2 occurred in patients with reactive arthritis in the same high frequency as did HL‐A 27, but this antigen is present in 55% of Finns. HL‐A 27 negative patients usually had a mild or somewhat atypical disease.
ISSN:0004-3591
1529-0131
DOI:10.1002/art.1780170505