Familial Erythema Nodosum

Erythema nodosum (EN) is a hypersensitivity reaction associated with many diseases. We describe a family in which 4 sisters had acute or recurrent EN. HLA typing showed a common haplotype in the affected members of the family. A review of familial EN and HLA distribution in EN is presented.

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Bibliographic Details
Published in:Arthritis and rheumatism 1991-09, Vol.34 (9), p.1177-1179
Main Authors: Elkayam, Ori, Caspi, Dan, Segal, Rafael, Brautbar, Chaim, Ben‐Chetrit, Eldad, Yaron, Michael
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Bacterial diseases
Biological and medical sciences
Ent and stomatologic bacterial diseases
Erythema Nodosum - blood
Erythema Nodosum - genetics
Erythema Nodosum - immunology
Family Health
Female
Haplotypes - immunology
HLA Antigens - immunology
Human bacterial diseases
Humans
Infectious diseases
Medical sciences
Middle Aged
Pedigree
Recurrence
Serotyping
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Description
Summary:Erythema nodosum (EN) is a hypersensitivity reaction associated with many diseases. We describe a family in which 4 sisters had acute or recurrent EN. HLA typing showed a common haplotype in the affected members of the family. A review of familial EN and HLA distribution in EN is presented.
ISSN:0004-3591
1529-0131
DOI:10.1002/art.1780340915