In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa

Ejaculated, density purified, human spermatozoa were exposed to pulsed 900 MHz GSM mobile phone radiation at two specific absorption rate levels (SAR 2.0 and 5.7 W/kg) and compared with controls over time. Change in sperm mitochondrial membrane potential was analysed using flow cytometry. Sperm moti...

Full description

Saved in:
Bibliographic Details
Published in:Bioelectromagnetics 2008-05, Vol.29 (4), p.268-276
Main Authors: Falzone, Nadia, Huyser, Carin, Fourie, Francois, Toivo, Tim, Leszczynski, Dariusz, Franken, Daniel
Format: Article
Language:English
Subjects:
CASA
Cell Phone
Cells, Cultured
Dose-Response Relationship, Radiation
human spermatozoa
Humans
Membrane Potential, Mitochondrial - physiology
Membrane Potential, Mitochondrial - radiation effects
Microwaves
mitochondrial membrane potential
mobile phone radiation
Radiation Dosage
Sperm Motility - physiology
Sperm Motility - radiation effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3
cites cdi_FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3
container_end_page 276
container_issue 4
container_start_page 268
container_title Bioelectromagnetics
container_volume 29
creator Falzone, Nadia
Huyser, Carin
Fourie, Francois
Toivo, Tim
Leszczynski, Dariusz
Franken, Daniel
description Ejaculated, density purified, human spermatozoa were exposed to pulsed 900 MHz GSM mobile phone radiation at two specific absorption rate levels (SAR 2.0 and 5.7 W/kg) and compared with controls over time. Change in sperm mitochondrial membrane potential was analysed using flow cytometry. Sperm motility was determined by computer assisted sperm analysis (CASA). There was no effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential. This was also the case for all kinematic parameters assessed at a SAR of 2.0 W/kg. However, over time, the two kinematic parameters straight line velocity (VSL) and beat‐cross frequency (BCF) were significantly impaired (P 
doi_str_mv 10.1002/bem.20390
format article
fullrecord <record><control><sourceid>istex_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_bem_20390</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_WNG_XN419RM1_4</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3</originalsourceid><addsrcrecordid>eNp1kN9LwzAQx4MoOqcP_gOSVx-ql6Zt0kcVnYNNwR-4t5A2KUaXpqSZuv31dnbqk3BwcHzuc9wXoSMCpwQgPiu0PY2B5rCFBiSNSUR4NttGAyA5i3iSxXtov21fAYBzoLtoj3CS0SSBAVqMa_xugndYV5UuA3YVbhbzViucA-DpzQqPHqbYS2VkMK7GXVkTXPniauWNnGOrbeFlrXHjgq7DeiRrha0LZm7Cci18WVhZ47bR3srgVk4eoJ1KdkcON32Inq6vHi9vosndaHx5PolKyhhERQmcKMqVJJRLyGicV1mex0kGvFS6Yrz7uSIpZ8BSmaZKqjKnDLRKCQVZ0iE66b2ld23rdSUab6z0S0FArKMTXXTiO7qOPe7ZZlFYrf7ITVYdcNYDH2aul_-bxMXV9EcZ9RumDfrzd0P6N5ExylLxfDsSs9uE5PdTIhL6BcF1h1g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa</title><source>Wiley</source><creator>Falzone, Nadia ; Huyser, Carin ; Fourie, Francois ; Toivo, Tim ; Leszczynski, Dariusz ; Franken, Daniel</creator><creatorcontrib>Falzone, Nadia ; Huyser, Carin ; Fourie, Francois ; Toivo, Tim ; Leszczynski, Dariusz ; Franken, Daniel</creatorcontrib><description>Ejaculated, density purified, human spermatozoa were exposed to pulsed 900 MHz GSM mobile phone radiation at two specific absorption rate levels (SAR 2.0 and 5.7 W/kg) and compared with controls over time. Change in sperm mitochondrial membrane potential was analysed using flow cytometry. Sperm motility was determined by computer assisted sperm analysis (CASA). There was no effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential. This was also the case for all kinematic parameters assessed at a SAR of 2.0 W/kg. However, over time, the two kinematic parameters straight line velocity (VSL) and beat‐cross frequency (BCF) were significantly impaired (P &lt; 0.05) after the exposure at SAR 5.7 W/kg and no exposure by time interaction was present. This result should not be ascribed to thermal effects, due to the cooling methods employed in the RF chamber and temperature control within the incubator. Bioelectromagnetics 29:268–276, 2008. © 2007 Wiley‐Liss, Inc.</description><identifier>ISSN: 0197-8462</identifier><identifier>EISSN: 1521-186X</identifier><identifier>DOI: 10.1002/bem.20390</identifier><identifier>PMID: 18163440</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>CASA ; Cell Phone ; Cells, Cultured ; Dose-Response Relationship, Radiation ; human spermatozoa ; Humans ; Membrane Potential, Mitochondrial - physiology ; Membrane Potential, Mitochondrial - radiation effects ; Microwaves ; mitochondrial membrane potential ; mobile phone radiation ; Radiation Dosage ; Sperm Motility - physiology ; Sperm Motility - radiation effects</subject><ispartof>Bioelectromagnetics, 2008-05, Vol.29 (4), p.268-276</ispartof><rights>Copyright © 2007 Wiley‐Liss, Inc.</rights><rights>(c) 2007 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3</citedby><cites>FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18163440$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Falzone, Nadia</creatorcontrib><creatorcontrib>Huyser, Carin</creatorcontrib><creatorcontrib>Fourie, Francois</creatorcontrib><creatorcontrib>Toivo, Tim</creatorcontrib><creatorcontrib>Leszczynski, Dariusz</creatorcontrib><creatorcontrib>Franken, Daniel</creatorcontrib><title>In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa</title><title>Bioelectromagnetics</title><addtitle>Bioelectromagnetics</addtitle><description>Ejaculated, density purified, human spermatozoa were exposed to pulsed 900 MHz GSM mobile phone radiation at two specific absorption rate levels (SAR 2.0 and 5.7 W/kg) and compared with controls over time. Change in sperm mitochondrial membrane potential was analysed using flow cytometry. Sperm motility was determined by computer assisted sperm analysis (CASA). There was no effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential. This was also the case for all kinematic parameters assessed at a SAR of 2.0 W/kg. However, over time, the two kinematic parameters straight line velocity (VSL) and beat‐cross frequency (BCF) were significantly impaired (P &lt; 0.05) after the exposure at SAR 5.7 W/kg and no exposure by time interaction was present. This result should not be ascribed to thermal effects, due to the cooling methods employed in the RF chamber and temperature control within the incubator. Bioelectromagnetics 29:268–276, 2008. © 2007 Wiley‐Liss, Inc.</description><subject>CASA</subject><subject>Cell Phone</subject><subject>Cells, Cultured</subject><subject>Dose-Response Relationship, Radiation</subject><subject>human spermatozoa</subject><subject>Humans</subject><subject>Membrane Potential, Mitochondrial - physiology</subject><subject>Membrane Potential, Mitochondrial - radiation effects</subject><subject>Microwaves</subject><subject>mitochondrial membrane potential</subject><subject>mobile phone radiation</subject><subject>Radiation Dosage</subject><subject>Sperm Motility - physiology</subject><subject>Sperm Motility - radiation effects</subject><issn>0197-8462</issn><issn>1521-186X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNp1kN9LwzAQx4MoOqcP_gOSVx-ql6Zt0kcVnYNNwR-4t5A2KUaXpqSZuv31dnbqk3BwcHzuc9wXoSMCpwQgPiu0PY2B5rCFBiSNSUR4NttGAyA5i3iSxXtov21fAYBzoLtoj3CS0SSBAVqMa_xugndYV5UuA3YVbhbzViucA-DpzQqPHqbYS2VkMK7GXVkTXPniauWNnGOrbeFlrXHjgq7DeiRrha0LZm7Cci18WVhZ47bR3srgVk4eoJ1KdkcON32Inq6vHi9vosndaHx5PolKyhhERQmcKMqVJJRLyGicV1mex0kGvFS6Yrz7uSIpZ8BSmaZKqjKnDLRKCQVZ0iE66b2ld23rdSUab6z0S0FArKMTXXTiO7qOPe7ZZlFYrf7ITVYdcNYDH2aul_-bxMXV9EcZ9RumDfrzd0P6N5ExylLxfDsSs9uE5PdTIhL6BcF1h1g</recordid><startdate>200805</startdate><enddate>200805</enddate><creator>Falzone, Nadia</creator><creator>Huyser, Carin</creator><creator>Fourie, Francois</creator><creator>Toivo, Tim</creator><creator>Leszczynski, Dariusz</creator><creator>Franken, Daniel</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200805</creationdate><title>In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa</title><author>Falzone, Nadia ; Huyser, Carin ; Fourie, Francois ; Toivo, Tim ; Leszczynski, Dariusz ; Franken, Daniel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>CASA</topic><topic>Cell Phone</topic><topic>Cells, Cultured</topic><topic>Dose-Response Relationship, Radiation</topic><topic>human spermatozoa</topic><topic>Humans</topic><topic>Membrane Potential, Mitochondrial - physiology</topic><topic>Membrane Potential, Mitochondrial - radiation effects</topic><topic>Microwaves</topic><topic>mitochondrial membrane potential</topic><topic>mobile phone radiation</topic><topic>Radiation Dosage</topic><topic>Sperm Motility - physiology</topic><topic>Sperm Motility - radiation effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Falzone, Nadia</creatorcontrib><creatorcontrib>Huyser, Carin</creatorcontrib><creatorcontrib>Fourie, Francois</creatorcontrib><creatorcontrib>Toivo, Tim</creatorcontrib><creatorcontrib>Leszczynski, Dariusz</creatorcontrib><creatorcontrib>Franken, Daniel</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Bioelectromagnetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Falzone, Nadia</au><au>Huyser, Carin</au><au>Fourie, Francois</au><au>Toivo, Tim</au><au>Leszczynski, Dariusz</au><au>Franken, Daniel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa</atitle><jtitle>Bioelectromagnetics</jtitle><addtitle>Bioelectromagnetics</addtitle><date>2008-05</date><risdate>2008</risdate><volume>29</volume><issue>4</issue><spage>268</spage><epage>276</epage><pages>268-276</pages><issn>0197-8462</issn><eissn>1521-186X</eissn><abstract>Ejaculated, density purified, human spermatozoa were exposed to pulsed 900 MHz GSM mobile phone radiation at two specific absorption rate levels (SAR 2.0 and 5.7 W/kg) and compared with controls over time. Change in sperm mitochondrial membrane potential was analysed using flow cytometry. Sperm motility was determined by computer assisted sperm analysis (CASA). There was no effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential. This was also the case for all kinematic parameters assessed at a SAR of 2.0 W/kg. However, over time, the two kinematic parameters straight line velocity (VSL) and beat‐cross frequency (BCF) were significantly impaired (P &lt; 0.05) after the exposure at SAR 5.7 W/kg and no exposure by time interaction was present. This result should not be ascribed to thermal effects, due to the cooling methods employed in the RF chamber and temperature control within the incubator. Bioelectromagnetics 29:268–276, 2008. © 2007 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>18163440</pmid><doi>10.1002/bem.20390</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0197-8462
ispartof Bioelectromagnetics, 2008-05, Vol.29 (4), p.268-276
issn 0197-8462
1521-186X
language eng
recordid cdi_crossref_primary_10_1002_bem_20390
source Wiley
subjects CASA
Cell Phone
Cells, Cultured
Dose-Response Relationship, Radiation
human spermatozoa
Humans
Membrane Potential, Mitochondrial - physiology
Membrane Potential, Mitochondrial - radiation effects
Microwaves
mitochondrial membrane potential
mobile phone radiation
Radiation Dosage
Sperm Motility - physiology
Sperm Motility - radiation effects
title In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T02%3A56%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-istex_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=In%20vitro%20effect%20of%20pulsed%20900%20MHz%20GSM%20radiation%20on%20mitochondrial%20membrane%20potential%20and%20motility%20of%20human%20spermatozoa&rft.jtitle=Bioelectromagnetics&rft.au=Falzone,%20Nadia&rft.date=2008-05&rft.volume=29&rft.issue=4&rft.spage=268&rft.epage=276&rft.pages=268-276&rft.issn=0197-8462&rft.eissn=1521-186X&rft_id=info:doi/10.1002/bem.20390&rft_dat=%3Cistex_cross%3Eark_67375_WNG_XN419RM1_4%3C/istex_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3770-bc081d38da138a06329f69924608cdef78390f1587075a55dadc9370ed5130ac3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/18163440&rfr_iscdi=true