Oxygen transfer coefficients by dynamic model moment analysis

A new method to estimate the oxygen transfer coefficient (KLa) from the experimental dynamic response data is presented. Employing a linear model which allows for gas phase, diffusion film, and oxygen electrode dynamics, the first moment of the response curve is simply related to the sum of the mode...

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Bibliographic Details
Published in:Biotechnology and bioengineering 1977-06, Vol.19 (6), p.853-865
Main Authors: Dang, N. D. P., Karrer, D. A., Dunn, I. J.
Format: Article
Language:English
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Summary:A new method to estimate the oxygen transfer coefficient (KLa) from the experimental dynamic response data is presented. Employing a linear model which allows for gas phase, diffusion film, and oxygen electrode dynamics, the first moment of the response curve is simply related to the sum of the model parameters. Two separate experiments are used to characterize the measurement dynamics and to measure the unknown KLa parameter. The simple calculation procedure involves only measuring the area above the response curves.
ISSN:0006-3592
1097-0290
DOI:10.1002/bit.260190606