CBr 4 ‐Mediated Cross‐Dehydrogenative Coupling Reaction of Amines

A novel CBr 4 ‐mediated dehydrogenative Povarov/aromatization tandem reaction of glycine derivatives with alkenes, leading to complex quinoline derivatives, and a CBr 4 ‐mediated dehydrogenative CH functionalization of N ‐aryl tetrahydroisoquinolines with nucleophiles to form CC and CP bonds are...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry : a European journal 2015-04, Vol.21 (15), p.5723-5726
Main Authors: Huo, Congde, Xie, Haisheng, Wu, Mingxia, Jia, Xiaodong, Wang, Xicun, Chen, Fengjuan, Tang, Jing
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A novel CBr 4 ‐mediated dehydrogenative Povarov/aromatization tandem reaction of glycine derivatives with alkenes, leading to complex quinoline derivatives, and a CBr 4 ‐mediated dehydrogenative CH functionalization of N ‐aryl tetrahydroisoquinolines with nucleophiles to form CC and CP bonds are reported. The reactions were performed under very simple and mild reaction conditions; only CBr 4 was used as a promoter. A plausible mechanism involving a radical process is proposed.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201500453