Synthesis and Characteristics of Self‐Assembled Multifunctional Ln 3+ ‐DNA Hybrid Coordination Polymers

Owing to the unique catalytic, optical and magnetic properties, lanthanides (Ln) as multicomponent biomarkers, are widely used in the field of optical sensing, mass spectrometry and magnetic resonance imaging. As ligands, DNA molecules have good biocompatibility, high stability, cost efficiency, pro...

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Bibliographic Details
Published in:Chemistry : a European journal 2022-08, Vol.28 (43)
Main Authors: Han, Qingzhi, Zhang, Xinlian, Jia, Yijing, Guo, Shaoshi, Zhu, Jiale, Luo, Shirui, Ouyang, Jin
Format: Article
Language:English
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Summary:Owing to the unique catalytic, optical and magnetic properties, lanthanides (Ln) as multicomponent biomarkers, are widely used in the field of optical sensing, mass spectrometry and magnetic resonance imaging. As ligands, DNA molecules have good biocompatibility, high stability, cost efficiency, programmability and biodegradability. Based on the coordination‐driven self‐assembly between Ln ions (Ln 3+ ) and DNA molecules, a multifunctional Ln 3+ ‐DNA hybrid coordination polymers (CPs) were synthesized. Not only a series of different Ln 3+ (single Ln 3+ ) and DNA hybrid CPs were synthesized, but one hybrid CP contains two kinds of Ln 3+ was obtained. Besides, the synthetic CPs in cell fluorescence imaging and miRNA sensing also exhibited high performance. This work provides a novel idea for the synthesis of DNA based nanomaterials, which is promising for biologically‐related applications.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.202200281