Facile and Efficient Asymmetric Synthesis of α-Aminoalkylphosphonic Acids

An improved procedure for the asymmetric synthesis of α‐aminoalkylphosphonic acids using S‐2‐anilino‐methylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric y...

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Bibliographic Details
Published in:Chinese journal of chemistry 2005-12, Vol.23 (12), p.1671-1676
Main Authors: Yuan, Cheng-Ye, Chen, Qian-Yi
Format: Article
Language:English
Subjects:
aminophosphonic acid
anilinomethylpyrrolidine
asymmetric synthesis
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Summary:An improved procedure for the asymmetric synthesis of α‐aminoalkylphosphonic acids using S‐2‐anilino‐methylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric yields.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.200591671