Synthesis and Investigation of Soluble Polymer-supported Dendrimers

Poly(ethylene glycol) (PEG)‐supported dendrimers have been synthesized using 2,4,6‐trichloro‐1,3,5‐triazine (TCT) as dendrons and tris(hydroxymethyl)aminomethane as linkers with high loading capacity, excellent solubility and thermal stability by divergent method. The new synthesized PEG‐supported G...

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Bibliographic Details
Published in:Chinese journal of chemistry 2006-04, Vol.24 (4), p.585-587
Main Authors: Xie, Cheng, Lu, Cui-Fen, Chen, Zu-Xing, Yang, Gui-Chun
Format: Article
Language:English
Subjects:
dendrimer
liquid-phase synthesis
loading capacity
poly(ethylene glycol)
support
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Summary:Poly(ethylene glycol) (PEG)‐supported dendrimers have been synthesized using 2,4,6‐trichloro‐1,3,5‐triazine (TCT) as dendrons and tris(hydroxymethyl)aminomethane as linkers with high loading capacity, excellent solubility and thermal stability by divergent method. The new synthesized PEG‐supported G2.0 dendrimer has 10 times as large functional group loading capacity as commercial PEG3400 with overall yield 44.0%.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.200690112