Further New Cembrane Diterpenes from the Hainan Soft Coral Sarcophyton latum

Two new cembranoid diterpenes, diepoxysarcophytonene (1) and sarconphytonol (2), were isolated from the Hainan soft coral Sarcophyton latum. Their structures including relative stereochemistry were established by 1D and 2D NMR spectroscopic techniques. Compound 1 showed weak inhibitory activity agai...

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Bibliographic Details
Published in:Chinese journal of chemistry 2008-01, Vol.26 (1), p.150-152
Main Authors: YAN, Xiao-Hong, FENG, Lin-Yin, GUO, Yue-Wei
Format: Article
Language:English
Subjects:
cembrane diterpene
chemical constituent
Sarcophyton latum
soft coral
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Summary:Two new cembranoid diterpenes, diepoxysarcophytonene (1) and sarconphytonol (2), were isolated from the Hainan soft coral Sarcophyton latum. Their structures including relative stereochemistry were established by 1D and 2D NMR spectroscopic techniques. Compound 1 showed weak inhibitory activity against COX‐2 in vitro at the concentration of 10−5 µmol·L−1 with the inhibitory rate of 55%.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.200890011