Interpretation of p16 INK4a /Ki‐67 dual immunostaining for the triage of human papillomavirus‐positive women by experts and nonexperts in cervical cytology

In the current study, p16 INK4a /Ki‐67 immunostaining demonstrated good reproducibility and specificity when triaging women who were positive for the human papillomavirus. Dual‐staining interpretation can be performed, after brief training, even by staff who are not experts in the morphological inte...

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Published in:Cancer cytopathology 2015-04, Vol.123 (4), p.212-218
Main Authors: Allia, Elena, Ronco, Guglielmo, Coccia, Anna, Luparia, Patrizia, Macrì, Luigia, Fiorito, Corinna, Maletta, Francesca, Deambrogio, Cristina, Tunesi, Sara, De Marco, Laura, Gillio‐Tos, Anna, Sapino, Anna, Ghiringhello, Bruno
Format: Article
Language:English
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Summary:In the current study, p16 INK4a /Ki‐67 immunostaining demonstrated good reproducibility and specificity when triaging women who were positive for the human papillomavirus. Dual‐staining interpretation can be performed, after brief training, even by staff who are not experts in the morphological interpretation of cytology.
ISSN:1934-662X
1934-6638
DOI:10.1002/cncy.21511