Zika virus: A new human teratogen? Implications for women of reproductive age

In 2015 an unprecedented increase of reports of newborns with microcephaly in Brazil made news headlines around the world. A possible etiological association with prenatal maternal infection by Zika virus (ZIKV) was suggested based on temporal and geographic distribution of ZIKV infection and the su...

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Bibliographic Details
Published in:Clinical pharmacology and therapeutics 2016-07, Vol.100 (1), p.28-30
Main Authors: Schuler-Faccini, L, Sanseverino, MTV, Vianna, FSL, da Silva, AA, Larrandaburu, M, Marcolongo-Pereira, C, Abeche, AM
Format: Article
Language:English
Subjects:
Animals
Brazil - epidemiology
Female
Humans
Infant, Newborn
Microcephaly - epidemiology
Microcephaly - virology
Pregnancy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - virology
Zika Virus Infection - complications
Zika Virus Infection - epidemiology
Zika Virus Infection - therapy
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Summary:In 2015 an unprecedented increase of reports of newborns with microcephaly in Brazil made news headlines around the world. A possible etiological association with prenatal maternal infection by Zika virus (ZIKV) was suggested based on temporal and geographic distribution of ZIKV infection and the subsequent increase in the reports of microcephaly cases. Here we discuss ZIKV as a new human teratogen, with comments on potential treatment options.
ISSN:0009-9236
1532-6535
DOI:10.1002/cpt.386