Development of antiinflammatory therapy for Alzheimer's disease

Inflammatory mechanisms are active in the Alzheimer's disease (AD) brain. Studies that range from epidemiological surveys to therapeutic trials in transgenic mice provide growing support for the theory that antiinflammatory drugs may be useful in the prevention and/or treatment of the disease....

Full description

Saved in:
Bibliographic Details
Published in:Drug development research 2002-07, Vol.56 (3), p.421-427
Main Author: Aisen, Paul S.
Format: Article
Language:English
Subjects:
Alzheimer's disease
inflammation
nonsteroidal antiinflammatory drugs
therapeutic trials
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Inflammatory mechanisms are active in the Alzheimer's disease (AD) brain. Studies that range from epidemiological surveys to therapeutic trials in transgenic mice provide growing support for the theory that antiinflammatory drugs may be useful in the prevention and/or treatment of the disease. Randomized controlled trials in humans have not yet confirmed this theory. However, prevention and treatment trials continue to test specific antiinflammatory strategies for AD. Drug Dev. Res. 56:421–427, 2002. © 2002 Wiley‐Liss, Inc.
ISSN:0272-4391
1098-2299
DOI:10.1002/ddr.10094