Case-mix/risk adjustment of observational data: it all depends on the purpose of the data collection

Each year finds dramatic new developments in the pharmacological treatment of diseases. With the availability of numerous interventions for most diseases, the impact of a medication on the course of a disease is critically dependent on the case mix of the patients under study. This article focuses o...

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Bibliographic Details
Published in:Drug development research 2006-03, Vol.67 (3), p.202-207
Main Author: Goldfield, Norbert
Format: Article
Language:English
Subjects:
case-mix adjustment
outcomes management
risk assessment
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Summary:Each year finds dramatic new developments in the pharmacological treatment of diseases. With the availability of numerous interventions for most diseases, the impact of a medication on the course of a disease is critically dependent on the case mix of the patients under study. This article focuses on the different methods, in broad terms, available for case‐mix adjustment of populations of patients. After addressing definitional concerns, this report highlights the different types of case‐mix adjustments available for each type of health care encounter, ranging from ambulatory visits to population‐based measures to long‐term care. There is little or no crossover in the use of different case‐mix systems across different types of health care encounters. This article concludes with evolving trends in case mix and a case example in an effort to highlight the challenges and opportunities present in this ever‐changing field. Drug Dev. Res. 67:202‐207, 2006. © 2006 Wiley‐Liss, Inc.
ISSN:0272-4391
1098-2299
DOI:10.1002/ddr.20078