Cover Picture: Synthesis and Biological Evaluation of Macrosphelide Cores (Eur. J. Org. Chem. 19/2004)

The cover picture shows the structures of the bioactive natural macrolide, macrosphelide A (third structure from left) and its artificial analogues. The other structures exhibit different oxidation states at the allylic positions on the common 16‐membered ring skeleton. The antitumor activity increa...

Full description

Saved in:
Bibliographic Details
Published in:European journal of organic chemistry 2004-10, Vol.2004 (19), p.3945-3945
Main Authors: Ishihara, Kentaro, Kawaguchi, Takanori, Matsuya, Yuji, Sakurai, Hiroaki, Saiki, Ikuo, Nemoto, Hideo
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The cover picture shows the structures of the bioactive natural macrolide, macrosphelide A (third structure from left) and its artificial analogues. The other structures exhibit different oxidation states at the allylic positions on the common 16‐membered ring skeleton. The antitumor activity increases from left to right. This image reflects the importance of the oxygen functionalities for the bioactivity of naturally occurring macrosphelides, as discussed in the article by H. Nemoto et al. on p. 3973 ff.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.200490038