Highly Water-Soluble Carbaborane-Bridged Bis(glycophosphonates)

A facile synthesis of carbaboranediyl‐bis(glycophosphonates) and corresponding phosphonothioates is presented. These compounds show extraordinarily high water solubility and low cytotoxicity. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) The synthesis and properties of high...

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Bibliographic Details
Published in:European Journal of Organic Chemistry 2009-12, Vol.2009 (36), p.6301-6310
Main Authors: Stadlbauer, Sven, Lönnecke, Peter, Welzel, Peter, Hey-Hawkins, Evamarie
Format: Article
Language:English
Subjects:
Antitumor agents
B derivatives
Boron
Carbaboranes
Chemistry
Exact sciences and technology
Medicinal chemistry
Organic chemistry
Organometalloidal and organometallic compounds
Phosphonates
Preparations and properties
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Summary:A facile synthesis of carbaboranediyl‐bis(glycophosphonates) and corresponding phosphonothioates is presented. These compounds show extraordinarily high water solubility and low cytotoxicity. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) The synthesis and properties of highly water‐soluble meta‐ and para‐carbaborane‐containing bis(galactosyl phosphonates) are presented.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.200900813