Palladium-Catalyzed α-Selective Alkenylation of Imidazo[1,2-a]pyridines through Aerobic Cross-Dehydrogenative Coupling Reaction

The palladium‐catalyzed highly regioselective vinylation of imidazopyridines through a cross‐dehydrogenative coupling reaction was developed. The reaction proceeds with the aid of molecular oxygen as the sole oxidant. A series of branched α‐vinylated products were obtained with high efficiency. The...

Full description

Saved in:
Bibliographic Details
Published in:European journal of organic chemistry 2015-02, Vol.2015 (4), p.715-718
Main Authors: Ghosh, Monoranjan, Naskar, Aswini, Mitra, Shubhanjan, Hajra, Alakananda
Format: Article
Language:English
Subjects:
Alkenylation
C-C coupling
Dehydrogenation
Nitrogen heterocycles
Oxygen
Regioselectivity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The palladium‐catalyzed highly regioselective vinylation of imidazopyridines through a cross‐dehydrogenative coupling reaction was developed. The reaction proceeds with the aid of molecular oxygen as the sole oxidant. A series of branched α‐vinylated products were obtained with high efficiency. The palladium‐catalyzed highly regioselective vinylation of imidazopyridines through a cross‐dehydrogenative coupling reaction is explored. The reaction proceeds with the aid of molecular oxygen as the sole oxidant. A series of branched α‐vinylated products are obtained with high efficiency.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201403372