Front Cover: A Straightforward Sequential Approach for the Enantioselective Synthesis of Optically Active α‐Arylmethanol‐1,2,3‐Triazoles (Eur. J. Org. Chem. 40/2018)

The Front Cover shows a chiral arylmethanols bearing the 1,2,3‐triazole moiety, with a variety of di(hetero)arylmethanols, which do not contain any N‐heteroatom. Such molecules can be obtained by using a straightforward sequential approach based on the enantioselective alkynylation of aldehydes foll...

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Bibliographic Details
Published in:European journal of organic chemistry 2018-11, Vol.2018 (40), p.5464-5464
Main Authors: Andrade, Floyd C. D., Pugnal, Lucas V. B. L., Betim, Hugo L. I., Vani, Jéssica F., Zukerman‐Schpector, Julio, Schwab, Ricardo S.
Format: Article
Language:English
Online Access:Get full text
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Summary:The Front Cover shows a chiral arylmethanols bearing the 1,2,3‐triazole moiety, with a variety of di(hetero)arylmethanols, which do not contain any N‐heteroatom. Such molecules can be obtained by using a straightforward sequential approach based on the enantioselective alkynylation of aldehydes followed by a one‐pot two‐step desilylation/CuAAC, providing the products with excellent yields and high levels of enantioselectivity. More information can be found in the Full Paper by R. S. Schwab et al.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201801419