Electrochemical Determination of Sunscreens Agents in Cosmetic Using Square Wave Voltammetry

• Published in: Electroanalysis (New York, N.Y.) N.Y.), 2019-03, Vol.31 (3), p.496-503
• Main Authors: Lopes Neves, Raiane Aparecida, Moreira Araujo, Fausto, Siqueira Pacheco, Felipe, Chevitarese Azevedo, Gustavo, Costa Matos, Maria Auxiliadora, Camargo Matos, Renato
• Format: Article
• Language: English
• Subjects: 2-ethylhexyl-4-methoxycinnamate; benzophenone-3; camphor 4-methylbenzylidene; chemical analysis; suncare/UV protection
• ISSN: 1040-0397; 1521-4109
• DOI: 10.1002/elan.201800747

Sunscreen agents and in particular UV filters are compounds added in different cosmetic formulations, that has the function of preventing damage caused by sun exposition. Therefore, this paper proposes the development of a simple, fast and reliable electroanalytical method utilizing square wave voltammetry (SWV) to the determination of Benzophenone‐3 (BZ‐3), camphor 4‐methylbenzylidene (MBC) and 2‐ethylhexyl‐4‐methoxycinnamate (OMC) in cosmetic samples. The electrochemical system consisted of a cell with three electrodes: work – gold electrode modified, reference – Ag/AgCl(sat) and auxiliary – platinum, using as supporting electrolyte 4.0 mL of Britton Robinson Buffer 0.04 mol L−1 (pH=4.0), 1.0 mL of methanol and 5.50×10−4 mol L−1 of cetyltrimethylammonium bromide (CTAB). The method was validated using three commercial sunscreen samples and the results showed recovery values between 83 and 98 %. The average values found for the analysed samples were 3.49 % m/m (728 mg L−1) to BZ‐3, 0.56 % m/m (113 mg L−1) to MBC and 0.99 % m/m (208 mg L−1) to OMC. The detection (DL) and quantification (QL) limits were 0.47 mg L−1 and 1.56 mg L−1 to BZ‐3, 0.77 mg L−1 and 2.58 mg L−1 to MBC and 0.78 mg L−1 and 2.59 mg L−1 to OMC, respectively. The sunscreen protector samples were also evaluated by high‐performance liquid chromatography (HPLC) demonstrating a good correlation between the results and compared the results with allowed concentration.