Modified Cyclodextrins as Enantioselective Hosts for Amino Acids

Two modified β‐cyclodextrins, H‐2 and H‐3, having a flexible appended moiety were studied for the chiral discrimination of the enantiomers of various amino acids by means of fluorescence as signaling option. These hosts quenched the fluorescence intensities of amino acids upon binding. The d‐enantio...

Full description

Saved in:
Bibliographic Details
Published in:Helvetica chimica acta 2008-04, Vol.91 (4), p.753-758
Main Authors: Kumar, Vydyula Pavan, Suryanarayana, Iragavarapu, Nageswar, Yadavalli Venkata Durga, Rao, Kakulapati Rama
Format: Article
Language:English
Subjects:
Amino acids
Cyclodextrin
Enantiomer discrimination
Enantioselectivity factor
Stability constants
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two modified β‐cyclodextrins, H‐2 and H‐3, having a flexible appended moiety were studied for the chiral discrimination of the enantiomers of various amino acids by means of fluorescence as signaling option. These hosts quenched the fluorescence intensities of amino acids upon binding. The d‐enantiomers were better recognized by these hosts. The association constants (Ks) and enantioselectivity factors (α) of the host⋅guest complexes were calculated.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200890077