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Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using β-Cyclodextrin as a Catalyst in Water Under Neutral Conditions

Synthesis of substituted pyrroles in H2O by using β‐cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good‐to‐excellent yields (79–89%). The supramolecular catalysis of the reaction was studied usin...

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Bibliographic Details
Published in:Helvetica chimica acta 2009-10, Vol.92 (10), p.2118-2124
Main Authors: Murthy, Sabbavarapu Narayana, Madhav, Bandaru, Kumar, Akkiligunta Vijay, Rao, Kakulapati Rama, Nageswar, Yadavalli Venkata Durga
Format: Article
Language:English
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Summary:Synthesis of substituted pyrroles in H2O by using β‐cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good‐to‐excellent yields (79–89%). The supramolecular catalysis of the reaction was studied using 1H‐NMR spectroscopy. β‐Cyclodextrin can be recovered and reused several times without loss of activity.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200900098