Caragisides A - C, New Isoflavone Glucosides from Caragana conferta with Inhibition of Platelet Aggregation

Caragisides A–C (1–3, resp.), three new isoflavone glucosides, were isolated from the BuOH sub‐fraction of the EtOH extract of the whole plant of Caragana conferta, along with ononoside (4), reported for the first time from this species. The structures of the new compounds were elucidated by spectro...

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Bibliographic Details
Published in:Helvetica chimica acta 2011-03, Vol.94 (3), p.438-445
Main Authors: Nisar Khan, Amna, Fatima, Itrat, Malik, Abdul, Rasheed, Huma
Format: Article
Language:English
Subjects:
Anti-platelet-aggregation activity
Caragana conferta
Caragisides A - C
Glucosides
Isoflavone glucosides
Ononoside
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Summary:Caragisides A–C (1–3, resp.), three new isoflavone glucosides, were isolated from the BuOH sub‐fraction of the EtOH extract of the whole plant of Caragana conferta, along with ononoside (4), reported for the first time from this species. The structures of the new compounds were elucidated by spectroscopic techniques including MS and 2D‐NMR spectroscopy. Compounds 1–3 showed significant inhibition of platelet aggregation.
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.201000210