Two New Pentacyclic Triterpenoids from Centella asiatica

Two new pentacyclic triterpenoids, named centelloside D (1) and centelloside E (9), together with the seven known compounds 2–8, were isolated from the whole plants of Centella asiatica. Compound 5 was reported for the first time from this genus. Their structures were elucidated on the basis of chem...

Full description

Saved in:
Bibliographic Details
Published in:Helvetica chimica acta 2012-02, Vol.95 (2), p.255-260
Main Authors: Weng, Xiao-Xiang, Zhang, Jing, Gao, Wen, Cheng, Liang, Shao, Yan, Kong, De-Yun
Format: Article
Language:English
Subjects:
Centella asiatica
Centellosides D and E
Cytotoxic activity
Glycosides
Triterpenoids
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two new pentacyclic triterpenoids, named centelloside D (1) and centelloside E (9), together with the seven known compounds 2–8, were isolated from the whole plants of Centella asiatica. Compound 5 was reported for the first time from this genus. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D‐ and 2D‐NMR, and HR‐MS experiments, and by comparison with literature data. Compounds 1–4, 6, and 8 did not show any cytotoxicity against L929 (mouse embryonic fibroblast).
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.201100287