The effect of n-butyl 2-cyanoacrylate on liver function

n‐Butyl 2‐cyanoacrylate was implanted subcutaneously in dogs and eight different liver function tests were employed over a 6‐month period in order to determine the effect of the cyanoacrylate on liver function. The biochemical results indicated that all the values obtained were within the normal ran...

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Bibliographic Details
Published in:Journal of biomedical materials research 1970-03, Vol.4 (1), p.25-28
Main Authors: Houston, Stuart, Ousterhout, Douglas K., Sleeman, Kenneth H., Leonard, Fred
Format: Article
Language:English
Subjects:
Acrylic Resins - toxicity
Animals
Dogs
Hemostatics - toxicity
Liver - drug effects
Liver Function Tests
Tissue Adhesives - toxicity
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Summary:n‐Butyl 2‐cyanoacrylate was implanted subcutaneously in dogs and eight different liver function tests were employed over a 6‐month period in order to determine the effect of the cyanoacrylate on liver function. The biochemical results indicated that all the values obtained were within the normal range of values reported for the dog. Pathological studies on all vital organs showed that the subcutaneously implanted cyanoacrylate polymer did not appear to cause harmful effects on the vital organs.
ISSN:0021-9304
1097-4636
DOI:10.1002/jbm.820040104