Synthesis of 2-Coumarinyl and Spiroindolyl-5-Phenyl-1,3,4-Oxadiazoles

The 2H‐1‐benzo/naphthopyran‐2‐one‐4‐yl (un)substituted phenyl‐1,3,4‐oxadiazoles has been synthesized by the oxidative cyclization of benzoic acid hydrazides formed in situ by the condensation of the respective 2H‐1‐benzo/naphthopyran‐2‐one‐4‐carboxaldehyde and (un)substituted monobenzoyl hydrazide i...

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Bibliographic Details
Published in:Journal of the Chinese Chemical Society (Taipei) 2006-04, Vol.53 (2), p.367-373
Main Authors: Kenn, Rajesh Shashikant, Mashelkar, Uday Chandrakant, Rane, Deepak Manohar
Format: Article
Language:English
Subjects:
1,3,4‐Oxadiazole
2′-thiozolidine]-2
3-Phenyl-spiro[3H-indoline-3
3‐Phenyl‐spiro[3H‐indoline‐3,2′‐thiozolidine]‐2,4′‐(1 H)dione
4-Oxadiazole
4′-(1 H)dione
Benzopyran-2-one
Coumarin
Lead tetraoxide
Naphthopyran-2-one
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Summary:The 2H‐1‐benzo/naphthopyran‐2‐one‐4‐yl (un)substituted phenyl‐1,3,4‐oxadiazoles has been synthesized by the oxidative cyclization of benzoic acid hydrazides formed in situ by the condensation of the respective 2H‐1‐benzo/naphthopyran‐2‐one‐4‐carboxaldehyde and (un)substituted monobenzoyl hydrazide in moderate yields. Also, spiro[indoline‐thiozolidine]‐2,4′‐diones has been syhthesized in a similar way from 3‐phenyl‐spiro[3H‐indoline‐3,2′‐thiozolidine]‐2,4′‐(1 H)dione monohydrazide and (un)substituted benzaldehydes.
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.200600046