Synthesis and Reactions of Naphtho[1′,2′:4,5]Furo[3,2-b]Pyridine and Naphtho[1′,2′:4,5]Furo[3,2-d]Pyrimidine Derivatives

2‐Acyl‐3‐aminonaphtho[2,1‐b]furan (1) reacts with activated methylene such as malono nitrile or ethyl cyanoacetate to afford naphtho[1′,2′:4,5]furo[3,2‐b]pyridine 2a,b. Chloroacylation of the amino group in compound (1) gave compound 3 which reacts with different amines to produce compound 4....

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Bibliographic Details
Published in:Journal of the Chinese Chemical Society (Taipei) 2007-08, Vol.54 (4), p.1045-1052
Main Authors: Badr, M. Z. A., Kamal El-Dean, A. M., Moustafa, O. S., Zaki, R. M.
Format: Article
Language:English
Subjects:
Naphthofuran
Naphthofuropyridines
Naphthofuropyrimidines
Reactions
Synthesis
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Summary:2‐Acyl‐3‐aminonaphtho[2,1‐b]furan (1) reacts with activated methylene such as malono nitrile or ethyl cyanoacetate to afford naphtho[1′,2′:4,5]furo[3,2‐b]pyridine 2a,b. Chloroacylation of the amino group in compound (1) gave compound 3 which reacts with different amines to produce compound 4.
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.200700151