Synthesis of substituted pyrimidine using ZnFe 2 O 4 nanocatalyst via one pot multi‐component reaction ultrasonic irradiation

A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe 2 O 4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction of benzimidazole ( 1 ), substituted aromatic aldehyde ( 2a‐j ) an...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 2020-09, Vol.57 (9), p.3326-3333
Main Authors: Chavan, Pravin, Bangale, Sachin, Pansare, Dattatraya, Shelke, Rohini, Jadhav, Shivaji, Tupare, Shrikrushna, Kamble, Dhanraj, Rai, Megha
Format: Article
Language:English
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Summary:A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe 2 O 4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction of benzimidazole ( 1 ), substituted aromatic aldehyde ( 2a‐j ) and malononitrile ( 3 ) under ultrasonic irradiations. Significance of this synthetic approach is short reaction time, easy handling, simplicity, efficiency, high yield, and recoverable catalyst.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.4048