Synthesis, structure and reactivity of imidazo[1,2-a][1,8]naphthyridines

The synthesis and reactivity of imidazo[1,2‐a][1,8]naphthyridines are reported. Electrophilic substitution reactions were studied and the site of the reaction was established with the aid of high‐field 1H and 13C nmr spectra. The experimental C‐1 position reaction was correlated with a CNDO/2 calcul...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 1997-05, Vol.34 (3), p.765-771
Main Authors: Gueiffier, Alain, Viols, Henri, Blache, Yves, Chapat, Jean Pierre, Chavignon, Olivier, Teulade, Jean Claude, Fauvelle, Florence, Grassy, Gérard, Dauphin, Gérard
Format: Article
Language:English
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Summary:The synthesis and reactivity of imidazo[1,2‐a][1,8]naphthyridines are reported. Electrophilic substitution reactions were studied and the site of the reaction was established with the aid of high‐field 1H and 13C nmr spectra. The experimental C‐1 position reaction was correlated with a CNDO/2 calculations.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570340311