The synthesis of azahomotryptophane derivatives. The transformation of N-trifluoroacetyl-5-bromo-4-oxonorvaline methyl ester into 4-(imidazo[1,2-a]azinyl-3)-4-oxohomoalanine derivatives

Azatryptophane homologues, 4‐(imidazo[1,2‐a]pyridinyl‐3)‐ 9a‐9f and 4‐(imidazo[1,2‐a]pyrimidinyl‐3)‐4‐oxohomoalanine derivatives 9g‐91, were prepared from N,N‐dimethyl‐N′‐(pyridinyl‐2)‐ 6a‐6f and N,N‐dimethyl‐N‐(pyriniidinyl‐2)formamidines 6g‐6i, and (S)‐N‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline meth...

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Published in:Journal of heterocyclic chemistry 1997-05, Vol.34 (3), p.853-856
Main Authors: Škof, Marko, Svete, Jurij, Stanovnik, Branko
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Language:English
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cited_by cdi_FETCH-LOGICAL-c3293-a97b103ead9bd9570fa391de6ad949e4d44931a79156a5dd9f4ec1b972d091a63
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container_title Journal of heterocyclic chemistry
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creator Škof, Marko
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description Azatryptophane homologues, 4‐(imidazo[1,2‐a]pyridinyl‐3)‐ 9a‐9f and 4‐(imidazo[1,2‐a]pyrimidinyl‐3)‐4‐oxohomoalanine derivatives 9g‐91, were prepared from N,N‐dimethyl‐N′‐(pyridinyl‐2)‐ 6a‐6f and N,N‐dimethyl‐N‐(pyriniidinyl‐2)formamidines 6g‐6i, and (S)‐N‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl ester (2) and its (R,S)‐isomer.
doi_str_mv 10.1002/jhet.5570340323
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title The synthesis of azahomotryptophane derivatives. The transformation of N-trifluoroacetyl-5-bromo-4-oxonorvaline methyl ester into 4-(imidazo[1,2-a]azinyl-3)-4-oxohomoalanine derivatives
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