A convenient method for the synthesis of six-membered heterocyclic enaminones

Enaminones are widely employed in the synthesis of heterocycles, however heterocyclic enaminones and their use in the synthesis of more complex systems have been less studied. The reaction between 4‐chloroacetylacetate and aliphatic or aromatic 1,2‐aminoalcohols, 1,2‐aminothiols or 1,2‐diamines, yie...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 1999-07, Vol.36 (4), p.1097-1099
Main Authors: Puebla, Pilar, Honores, Zoila, Medarde, Manuel, Caballero, Esther, Feliciano, Arturo San, Morán, Lourdes
Format: Article
Language:English
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Summary:Enaminones are widely employed in the synthesis of heterocycles, however heterocyclic enaminones and their use in the synthesis of more complex systems have been less studied. The reaction between 4‐chloroacetylacetate and aliphatic or aromatic 1,2‐aminoalcohols, 1,2‐aminothiols or 1,2‐diamines, yields in one pot a six‐membered 1,4‐heterocyclic system containing the enaminone moiety.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570360445