Synthesis and characterization of new biologically active 2-(1,3-disubstituted pyrazolyl)chromones and corresponding pyrimidine, thiopyrimidine, pyrazolyl derivatives

A series of 2‐(1‐methyl‐3‐n‐propylpyrazol‐5‐yl)‐chromones with interesting Phosphodiesterase IV inhibitition activities were synthesized. Different derivatives of the titled compounds like aminopyrimidine, thiopyrimidine, pyrazolyl were synthesized and their Phosphodiesterase IV inhibitition activit...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 2004-07, Vol.41 (4), p.541-548
Main Authors: Joshia, N. S., Karale, B. K., Gill, C. H., Bhirud, S. B.
Format: Article
Language:English
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Summary:A series of 2‐(1‐methyl‐3‐n‐propylpyrazol‐5‐yl)‐chromones with interesting Phosphodiesterase IV inhibitition activities were synthesized. Different derivatives of the titled compounds like aminopyrimidine, thiopyrimidine, pyrazolyl were synthesized and their Phosphodiesterase IV inhibitition activities were checked.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570410410