Vilsmeier-Haack formylation of acetonitrile revisited: Synthesis of novel pyrazolo[1,5-a]pyrimidines and triazolo[1,5-a]pyrimidine

Vilsmeier–Haack formylation of acetonitrile using dimethylformamide and phosphorus oxychloride leading to a novel intermediate, N‐((E)‐3‐(dimethylamino)‐2‐formylacryloyl)formamidine 2 and its utility in the synthesis of pyrimidine‐fused heterocycles such as pyrazolo[1,5‐a]pyrimidines and triazolo[1,...

Full description

Saved in:
Bibliographic Details
Published in:Journal of heterocyclic chemistry 2009-03, Vol.46 (2), p.327-331
Main Authors: Ghagare, Maruti G., Birari, Dilip R., Shelar, Deepak P., Toche, Raghunath B., Jachak, Madhukar N.
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Vilsmeier–Haack formylation of acetonitrile using dimethylformamide and phosphorus oxychloride leading to a novel intermediate, N‐((E)‐3‐(dimethylamino)‐2‐formylacryloyl)formamidine 2 and its utility in the synthesis of pyrimidine‐fused heterocycles such as pyrazolo[1,5‐a]pyrimidines and triazolo[1,5‐a]pyrimidine is reported. J. Heterocyclic Chem., 46, 327 (2009).
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.76