Liver transplantation versus liver resection for the treatment of hepatocellular carcinoma

Purpose Liver resection (LR) and liver transplantation (LT) are considered the only two potentially curative treatments for hepatocellular carcinoma (HCC). Recently, there has been an intense debate as to whether LR or LT is the optimal initial treatment for patients with Child A or B cirrhosis. The...

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Bibliographic Details
Published in:Journal of surgical oncology 2010-01, Vol.101 (1), p.47-53
Main Authors: Lee, Kyung Keun, Kim, Dong Goo, Moon, In Sung, Lee, Myung Duk, Park, Jung Hyun
Format: Article
Language:English
Subjects:
Adult
Aged
Carcinoma, Hepatocellular - mortality
Carcinoma, Hepatocellular - surgery
child A or B
Female
Hepatectomy
hepatocellular carcinoma
Humans
Liver Neoplasms - mortality
Liver Neoplasms - surgery
liver resection
Liver Transplantation
Male
Middle Aged
Neoplasm Recurrence, Local
Survival Rate
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Summary:Purpose Liver resection (LR) and liver transplantation (LT) are considered the only two potentially curative treatments for hepatocellular carcinoma (HCC). Recently, there has been an intense debate as to whether LR or LT is the optimal initial treatment for patients with Child A or B cirrhosis. The aim of this study was to compare the results of LR and LT in patients with HCC and with Child A or B cirrhosis in a single center over a 10‐year period. Method Seventy‐eight patients were treated with LT and 130 were treated with LR. We evaluated patient characteristics, short‐term results such as hospital stay, postoperative complication, mortality, and long‐term results such as overall and recurrence‐free survival and recurrence. Results The hospital stay of the LT group was significantly longer than that of the LR group (P 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.21415