Morphological foundation of hydrogel use for vascular occlusion

Morphological grounds presented here show, that hydrogel with a 2‐hydroxyethyl methacrylate basis is a suitable material for vascular occlusion with therapeutic purposes. It has been shown, that hydrogel emboli neither injure, nor irritate the blood vessel wall; they promote thrombogenesis in the lo...

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Bibliographic Details
Published in:Die Makromolekulare Chemie 1985-01, Vol.9 (S19851), p.145-150
Main Authors: Skuba, N. D., Kálal, J., Vacík, I., Voroncova, O. S.
Format: Article
Language:English
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Summary:Morphological grounds presented here show, that hydrogel with a 2‐hydroxyethyl methacrylate basis is a suitable material for vascular occlusion with therapeutic purposes. It has been shown, that hydrogel emboli neither injure, nor irritate the blood vessel wall; they promote thrombogenesis in the localization sites and are preserved in the vascular lumen for a period necessary for the manifestation of the therapeutic occlusive effect. The hydrogel property to swell directly in the vascular lumen, as well as to promote blood clotting, is a factor providing for reliable occlusion.
ISSN:0025-116X
0025-116X
DOI:10.1002/macp.1985.020091985119