Micro-/Nanoscale Structuring of Cell-Culture Substrates with Fluorocarbon Plasmas

We describe the tailoring of polymer surfaces with CFx composition and roughness/density of different micro‐/nanometric relieves (ribbons, petals, domes, dots) tuned independently in low pressure plasma deposition and etching processes. Similarity of outer chemical composition grants the comparison...

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Bibliographic Details
Published in:Plasma processes and polymers 2010-03, Vol.7 (3-4), p.212-223
Main Authors: Di Mundo, Rosa, Gristina, Roberto, Sardella, Elaisa, Intranuovo, Francesca, Nardulli, Marina, Milella, Antonella, Palumbo, Fabio, d'Agostino, Riccardo, Favia, Pietro
Format: Article
Language:English
Subjects:
biomedical applications
cell-culture
fluorocarbon
micro-/nanotexturing
plasma deposition
plasma etching
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Summary:We describe the tailoring of polymer surfaces with CFx composition and roughness/density of different micro‐/nanometric relieves (ribbons, petals, domes, dots) tuned independently in low pressure plasma deposition and etching processes. Similarity of outer chemical composition grants the comparison of cell culture results to analyze the impact of topographical features on cellular behavior. Such surfaces are of interest for biomedical substrates since tuning their surface composition and morphology can drive the behavior of cells in contact with them. Ribbon‐like, dome/petal‐like and nanodotted surfaces tailored with low pressure plasma deposition and etching processes have been tested as culture substrates of osteoblast cell lines. Such surfaces are of interest for biomedical applications since tuning their surface morphology can drive cell behavior, which is properly investigated once the outer fluorocarbon chemistry has been uniformed.
ISSN:1612-8850
1612-8869
DOI:10.1002/ppap.200900112