Radioprotective effect of sugar cane extract in chickens

To evaluate the radioprotective effect of sugar cane extract (SCE), SCE was orally administered into the crop of 3‐week‐old chickens for 3 consecutive days before or after x‐ray radiation at a dose of 500 mg/kg/day. The survival rate of SCE administered chickens before x‐ray radiation at a dose of 9...

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Bibliographic Details
Published in:Phytotherapy research 2005-06, Vol.19 (6), p.496-500
Main Authors: Amer, S, Na, K.J, Motobu, M, El-Abasy, M, Nakamura, K, Koge, K, Hirota, Y
Format: Article
Language:English
Subjects:
Administration, Oral
Animals
Biological and medical sciences
chicken
Chickens
General pharmacology
Jejunum - pathology
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Radiation Dosage
Radiation Injuries, Experimental - prevention & control
Radiation-Protective Agents - administration & dosage
Radiation-Protective Agents - pharmacology
Radiation-Protective Agents - therapeutic use
radioprotection
Saccharum
Saccharum officinarum L
sugar cane extract
x-ray
X-Rays
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Summary:To evaluate the radioprotective effect of sugar cane extract (SCE), SCE was orally administered into the crop of 3‐week‐old chickens for 3 consecutive days before or after x‐ray radiation at a dose of 500 mg/kg/day. The survival rate of SCE administered chickens before x‐ray radiation at a dose of 920 rad increased to 68.8% when compared with that of the irradiated control (50%). Histopathological examination revealed the intestine of SCE administered chickens to have mild to moderate pathological changes, when compared with that of the irradiated control animals. Copyright © 2005 John Wiley & Sons, Ltd.
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.1688