Developing New Cleavage Strategies in a Fluorous Phase Pummerer Cyclative-Capture Approach for the Synthesis of N-Heterocycles

An efficient, oxidative cleavage of a sulfur linker has been developed for the fluorous phase synthesis of N‐heterocycles. The new cleavage strategy facilitates the synthesis of products containing diverse structural features.

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Bibliographic Details
Published in:QSAR & combinatorial science 2006-09, Vol.25 (8-9), p.709-712
Main Authors: McCormick, Rosemary A., James, Karen M., Willetts, Nigel, Procter, David J.
Format: Article
Language:English
Subjects:
Fluorous phase
Linkers
Oxidative cleavage
Pummerer
Sulfur
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Description
Summary:An efficient, oxidative cleavage of a sulfur linker has been developed for the fluorous phase synthesis of N‐heterocycles. The new cleavage strategy facilitates the synthesis of products containing diverse structural features.
ISSN:1611-020X
1611-0218
DOI:10.1002/qsar.200640050