Silver Patterned Supramolecular Liquid Crystalline Gels as Electrochemical Sensor of Tyrosine

• Published in: ChemistrySelect (Weinheim) 2017-01, Vol.2 (1), p.320-328
• Main Authors: K.Narayanan, Rohini, Sadanandhan, Neethu K., Devaki, Sudha J.
• Format: Article
• Language: English
• Subjects: Electrochemical sensing; Gels; Liquid crystalline; Silver; Supramolecular; Tyrosine
• ISSN: 2365-6549; 2365-6549
• DOI: 10.1002/slct.201601085

Here, we have prepared silver nanoparticle patterned functional liquid crystalline gels (SFLAG) through self‐assembly process. The surface plasmon energy of SFLAGs were observed at ∼ 420 nm and FCC lattices of silver particles were confirmed with XRD. Formation of liquid crystalline gel phase was studied by microscopic techniques and rheology. Enhancement in the conductance of SFLAG modified glassy carbon electrode (SFLAG/GCE) was studied with electrochemical impedance spectroscopy. Finally its application is demonstrated as an electrochemical sensor for the oxidation of tyrosine using electrochemical techniques such as cyclic voltammetry, differential pulse voltammetry and chronoamperometry with a high current response and lower detection limit (10 nM). Electrochemical sensor performances such as interference of various analytes, selectivity, repeatability, storage stability and the real sample analysis with human blood serum were performed. All these excellent properties of SFLAG/GCE can be exploited as an electrochemical sensor for the analytical detection of tyrosine which is a biomarker for the early detection of cancer. A supramolecular silver nanoparticles patterned liquid crystalline hydrogel formed by the self‐assembly of laponite and a low molecular weight organic gelator as an electrochemical sensor for tyrosine