Chiral Hydroxamic Acid Ligands in Asymmetric Synthesis: The Evolution of Metal‐Catalyzed Oxidation Reactions

Asymmetric oxidation reaction is one of the significant pathways in stereoselective reactions, which is a prominent performer in academic and industrial research. However, ligands are vital for planning an ideal metal‐catalyzed asymmetric oxidation reaction as they interact with the metal to constru...

Full description

Saved in:
Bibliographic Details
Published in:ChemistrySelect (Weinheim) 2023-03, Vol.8 (11), p.n/a
Main Authors: Janardan Pawar, Tushar, Bonilla‐Landa, Israel, Reyes‐Luna, Alfonso, Barrera‐Méndez, Felipe, Javier Enríquez‐Medrano, Francisco, Enrique Díaz‐de‐León‐Gómez, Ramón, Luis Olivares‐Romero, José
Format: Article
Language:English
Subjects:
Bishydroxamic acid
Enantioselective reaction
Hydroxamic acid
Ligand
Metal catalysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Asymmetric oxidation reaction is one of the significant pathways in stereoselective reactions, which is a prominent performer in academic and industrial research. However, ligands are vital for planning an ideal metal‐catalyzed asymmetric oxidation reaction as they interact with the metal to construct catalytically active metal complexes, which can catalyze numerous asymmetric reactions. Designing and synthesizing novel chiral ligands is essential for researchers in modern asymmetric synthesis. In this course, exploring the applicability and the survey of hydroxamic acid as a vital ligand has been presented, which is essential for various metal‐catalyzed transformations. In asymmetric metal‐catalysis, bishydroxamic acid is an essential ligand for the enantioselective oxidation reactions. These ligands can allow not only oxidation reactions but also epoxidation, dearomatization, ring‐closing, ring opening, 1,3‐dipolar cycloaddition, anti‐dihydroxylation and many more. In this minireview, the development and application of this ligand are discussed.
ISSN:2365-6549
2365-6549
DOI:10.1002/slct.202300555