Silicasome Nanocarriers: Development of Facile and Versatile Platinum Drug Delivering Silicasome Nanocarriers for Efficient Pancreatic Cancer Chemo‐Immunotherapy (Small 14/2021)

Effective delivery of activated oxaliplatin to pancreatic cancer achieved by a tailored silicasome nanocarrier is reported by Andre E. Nel, Huan Meng, and co‐workers in article number 2005993. This provides a strong immunogenic cell death stimulus that turns the “cold” immunological status into “hot...

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Bibliographic Details
Published in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2021-04, Vol.17 (14), p.n/a
Main Authors: Liu, Xiangsheng, Jiang, Jinhong, Chang, Chong Hyun, Liao, Yu‐Pei, Lodico, Jared J., Tang, Ivanna, Zheng, Emily, Qiu, Waveley, Lin, Matthew, Wang, Xiang, Ji, Ying, Mei, Kuo‐Ching, Nel, Andre E., Meng, Huan
Format: Article
Language:English
Subjects:
anti‐PD‐1 antibody
immunogenic cell death (ICD)
pancreatic cancer (PDAC)
platinum drug
silicasome nanocarrier
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Summary:Effective delivery of activated oxaliplatin to pancreatic cancer achieved by a tailored silicasome nanocarrier is reported by Andre E. Nel, Huan Meng, and co‐workers in article number 2005993. This provides a strong immunogenic cell death stimulus that turns the “cold” immunological status into “hot” at tumor site, enabling superior chemo‐immunotherapy synergy with anti‐PD‐1.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202170065