New stationary phase for capillary liquid chromatography based on polydimethylsiloxane immobilized onto a Monolithic Silica Support

A new stationary phase based on polydimethylsiloxane immobilized onto a monolithic silica support was prepared for performing reversed‐phase capillary liquid chromatography. Silica monoliths, using tetramethoxysilane as precursor, and hybrid monoliths, using tetramethoxysilane and methyltrimethoxysi...

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Bibliographic Details
Published in:Separation science plus 2018-05, Vol.1 (5), p.343-350
Main Authors: Pires, Fabiane, Otálora, Julie Alexandra Bautista, Bottoli, Carla Beatriz Grespan
Format: Article
Language:English
Subjects:
capillary liquid chromatography
polydimethylsiloxane
silica monoliths
thermal immobilization
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Summary:A new stationary phase based on polydimethylsiloxane immobilized onto a monolithic silica support was prepared for performing reversed‐phase capillary liquid chromatography. Silica monoliths, using tetramethoxysilane as precursor, and hybrid monoliths, using tetramethoxysilane and methyltrimethoxysilane as precursors, were prepared by the sol–gel process. Polydimethylsiloxane was deposited on the monolithic matrix and its immobilization was performed through thermal treatment. Characterization was made by field‐emission scanning electron microscopy and by chromatographic evaluation for the separation of six alkylbenzenes. An efficiency of 79 500 plates/m was reached for columns of 200 μm id, demonstrating that it would be a promising alternative to a reversed‐phase column in capillary liquid chromatography.
ISSN:2573-1815
2573-1815
DOI:10.1002/sscp.201800033