EFFECTS OF TH-2 TYPE CYTOKINES ON HUMAN AIRWAY EPITHELIAL CELLS: INTERLEUKINS-4, -5, AND -13

Proliferation and death of airway epithelial cells may be of importance in the pathogenesis of asthma. T-helper (Th)-2 response interleukins (IL)-4, -5, and -13 have the ability to induce proliferation of airway epithelial cells.

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Bibliographic Details
Published in:Cell biology international 2001-06, Vol.25 (6), p.563-566
Main Authors: Relova, A.J., Kampf, C., Roomans, G.M.
Format: Article
Language:English
Subjects:
airway epithelium
asthma
Asthma - immunology
Bronchi - cytology
Cell Division - drug effects
Cell Division - immunology
cell proliferation
Cell Survival - drug effects
Cell Survival - immunology
cytokines
Cytotoxicity Tests, Immunologic
Humans
inflammation
Interleukin-13 - pharmacology
Interleukin-4 - pharmacology
Interleukin-5 - pharmacology
Interleukins - pharmacology
Respiratory Mucosa - cytology
Respiratory Mucosa - drug effects
Respiratory Mucosa - immunology
Th2 Cells - immunology
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Description
Summary:Proliferation and death of airway epithelial cells may be of importance in the pathogenesis of asthma. T-helper (Th)-2 response interleukins (IL)-4, -5, and -13 have the ability to induce proliferation of airway epithelial cells.
ISSN:1065-6995
1095-8355
DOI:10.1006/cbir.2000.0687