Neuroprotective Effects of the Pyrrolopyrimidine U-104067F in 3-Acetylpyridine-Treated Rats

The neuroprotective effects of U-104067F [(9-(2-morpholinyl)ethyl)2,4-di-l-pyrrolidinyl-9H-pyrimidino(4,5-b)indole monohydrochloride hydrate], a pyrrolopyrimidine antioxidant, were investigated in 3-acetylpyridine (3-AP)-treated Wistar rats. A significant (P

Saved in:
Bibliographic Details
Published in:Experimental neurology 1996-07, Vol.140 (1), p.79-83
Main Authors: Sethy, Vimala H., Wu, Haiyan, Oostveen, Jo A., Hall, Edward D.
Format: Article
Language:English
Subjects:
Adenosine Triphosphate - metabolism
Animals
Biological and medical sciences
Cell Count - drug effects
Cyclic GMP - metabolism
Dose-Response Relationship, Drug
Male
Medical sciences
Neuropharmacology
Neuroprotective agent
Neuroprotective Agents - pharmacology
Pharmacology. Drug treatments
Pyridines - pharmacology
Pyrimidines - pharmacology
Pyrrolidines - pharmacology
Rats
Rats, Wistar
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The neuroprotective effects of U-104067F [(9-(2-morpholinyl)ethyl)2,4-di-l-pyrrolidinyl-9H-pyrimidino(4,5-b)indole monohydrochloride hydrate], a pyrrolopyrimidine antioxidant, were investigated in 3-acetylpyridine (3-AP)-treated Wistar rats. A significant (P
ISSN:0014-4886
1090-2430
DOI:10.1006/exnr.1996.0117